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This may impair monitoring based on total serum valproate levels

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The FDA label for cyanocobalamin injection warns that folic acid doses greater than 0.1 mg per day may produce a hematologic remission, the blood counts look better, but "neurologic manifestations will not be prevented with folic acid." That is why B12 deficiency needs to be identified and treated on its own, not covered over with a folate supplement